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Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice

Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice

June 27, 2025 Category: Blog

Only a few signaling pathways have been reported in germinal center (GC) B-cell proliferation and death.In this study, we showed that Loft Bin Storage a novel uncharacterized Gm614 protein is highly expressed in GC B cells from lupus-prone mice.Critically, ablation of this GC B-cell-specific Gm614 promoted GC B-cell death and mitigation of autoimmu

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Follow-up and outcome of the twelve-year experience in adult patients with acute promyelocytic leukemia

June 27, 2025 Category: Blog

Acute promyelocytic leukemia is a subtype of acute myeloid leukemia, characterized by the presence of neoplastic promyelocytes, due to the reciprocal balanced translocation between chromosomes 15 and 17.Currently, with Smart Home Accessories the use of agents that act directly on this molecular change, such as all-trans retinoic acid and arsenic tr

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Effect of non-stationary external forces on vibrations of composite pipelines conveying fluid

June 27, 2025 Category: Blog

The effect of non-stationary external forces on the vibration of pipelines made of composite materials is investigated in the paper.A mathematical model of composite pipeline vibration is developed, considering the viscosity properties of the structure and pipeline base material, axial forces, internal 20m Coaxial pressure, resistance forces, and e

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